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Research Ethics/Article Retraction

Clinical Trials/Clinical Practice

"Most major randomized, controlled trials before the year 2000 showed therapeutic benefits (Figure 1), according to data on NHLBI-funded trials for cardiovascular disease between 1970 and 2012. But after the year 2000, when the agency codified hypothesis pre-registration, trials mostly ended in null results. Useless drugs, with possible side effects, had almost certainly been approved, manufactured, and swallowed by Americans." --

New Science, blog post by Niko McCarty, 9/6/2022

Brook Jackson: Pfizer - Ventavia Research Group - ICON PLC